Even More of What's Hot in Immuno-Oncology Licensing

Posted by Steve Joseph on Nov 23, 2015 12:09:31 PM

immuno-oncology-part2-sm.jpgImmuno‑Oncology (I‑O) is a rapidly evolving field that focuses on the immune system in the fight against cancer. Today, surgery, radiation, and cytotoxic/targeted therapies are common treatment approaches in many advanced cancers. However, global mortality rates remain high for many patients with advanced tumors. The goal of Immuno-Oncology (I-O) research is to fulfill the unmet need for improving clinical outcomes in several advanced cancers by finding new ways to stop cancer from evading the immune system, thereby restoring the body's natural ability to recognize and eliminate cancer.

On October 6th, 2015 ShareVault presented a live web panel where the panelists discussed what was exciting in the immuno-oncology field. The discussion was so popular that we've decided to follow it up with a second web panel, "Even More of What's Hot in Immuno-Oncology Licensing

December 10th, 2015 from 2 - 3:15 EDT / 11 - 12:15 PDT. 

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Topics: Events

How to Organize a Due Diligence List for BioPharma Partnering

Posted by John Badger on Nov 5, 2015 9:48:00 AM


Given the rapid pace of innovation in today’s Life Science industry it has become more important than ever for biotech companies to align themselves with strategic partners in order to advance their most promising drug candidates toward market readiness. But successful BioPharma partnerships don't happen by chance and negotiating an out-licensing deal can be complex—especially when the company may also be progressing the clinical portfolio.

Life science companies attempting to optimize the commercialization of their assets often find the process daunting. In addition to determining the appropriate value of the asset and being prepared for negotiations, life science companies also often face the challenge of how to best organize and present all the data and documents to potential partners in order for them to make an informed decision.

The ideal platform for doing this is a virtual data room. A virtual data room not only keeps information secure, but also offers many other features that minimize risk, save time and increase the likelihood of completing successful transactions.

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Topics: Products

How to Redact Text or Images in a PDF

Posted by Phil Bandy on Nov 4, 2015 8:11:25 AM

Before distributing a PDF, you may want to delete confidential or sensitive personal information (such as credit card numbers, social security numbers or email addresses) that you don’t want to share. This is called “redaction.” Redaction is the process of permanently removing visible text and graphics from a document. Unfortunatlely, many people believe that redaction is simply drawing black boxes on top of text using PDF annotation tools. Although it looks very similar to redaction, drawing black rectangles over text or images does not prevent the reader from copying the text or graphics that are beneath the black rectanges. In other words, even if you can't see the information, it's still there and it's easy for a user to copy it. A proper redaction tool not only blacks-out the content, but also deletes the underlying text and images.

There are many horror stories related to sharing of PDFs that were not properly redacted.  Refer to this article on the American Bar Association website for more information on the dangers of improper redaction.

Fortunately, using Adobe Acrobat it’s quite simple to redact text or graphics from a PDF in order to remove sensitive information:

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Topics: Security

Shorten Loan Cycle Times, Increase Volume and Make Borrowers Happy

Posted by Anthony Wilson on Nov 3, 2015 12:45:15 PM

The evaluation and approval process in commercial lending involves comprehensive information gathering and financial analysis in order to make a sound judgment regarding the borrower’s financial stability and ability to repay the loan.

However, as anyone who has ever conducted due diligence knows, this process of “getting to know” the business, although simple in concept, is quite rigorous in practice.

Banks are highly regulated and operate on very thin margins so there is little room for write-offs and bad loans. When conducting due diligence on a borrower, banks must thoroughly investigate the entire business, not too dissimilar from an M&A process.

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Topics: Information

ShareVault Attends SoCalBio’s 2015 Investor Conference

Posted by Steve Joseph on Nov 2, 2015 8:00:00 AM

November 6 | 2015 - Long Beach, California

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Topics: Events

ShareVault Attends Pennsylvania Bio's "Life Sciences Future" Conference

Posted by Steve Joseph on Oct 28, 2015 8:56:59 AM

October 29-30th | 2015

This week ShareVault will be sponsoring Reverse Pitch Sessions and exhibiting at Pennsylvania Bio's "Life Sciences Future" conference at the Sheraton Downtown in Philadelphia. If you're going to be there, please stop by and see us.

Pennsylvania Bio was founded 25 years ago by a group of Biotech CEOs. Today the organization has grown to represent the entire life sciences industry—medical device companies, pharmaceutical companies, investment organizations, academic institutions, and a myriad of service industries that support the life sciences in Pennsylvania.

Pennsylvania Bio delivers two valuable services—public policy clout, and strategic connections that can advance you and your organization. Their public policy work in both Harrisburg and Washington ensures that all of their members are heard by those who make legislative decisions. Pennsylvania Bio also provides members with unparalleled networking opportunities to facilitate strategic connections. Their array of both large and small events throughout the year ensure that their members stay connected.

The "Life Sciences Future" conference was developed with the organization's diverse membership in mind—biopharma, medical device and diagnostics, healthcare IT, contract research organizations, medical research institutions, and the investment community. Their members actively help to develop the meeting agenda in order to ensure that content is relevant, engaging and thought provoking.

To learn more about how ShareVault can be a critical tool for partnering and licensing in life sciences, click here.

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Topics: Events

The Top 5 Ways a Good Data Room Helps You Collect Valuable Deal Intelligence [webinar]

Posted by John Badger on Oct 27, 2015 8:07:59 AM

Wednesday, October 28th, 2015 | 11:00-11:30am PDT / 2:00-2-30pm EDT

Most people don't realize that a data room can give you valuable deal intelligence, providing you with advance notice on topics of importance during negotiations, or tipping you off about who is the most interested party in a bidding war.

Most people only think a data room is important as an efficient and secure way to share documents with external parties during business transactions such as mergers, acquisitions, partnerships, equity fundraising, etc., but a good virtual data room can also provide amazingly valuable deal intelligence.

In fact, very few VDR's offer both page-level tracking and time-based monitoring of who's seen which pages of which documents, when and for how long. This granular reporting provides detailed audit trails for compliance and insightful business intelligence into your users' document review progress.

ShareVault's flexible and powerful reporting tools include a "heat map" display to clearly indicate with color-coding who's been the most active in your data room.

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Topics: Events

Gene Editing for Rare Disorders: How Promising is It?

Posted by Steve Joseph on Oct 12, 2015 12:21:41 PM

The ability to modify the nucleotide sequence of a genome with precision is a critical aspect of genome editing. That's been the challenge. But in the last five years great strides have been made as we’ve seen the development of TALENs, and more recently, CRISPRs. The advantage of these systems is that it has allowed a whole range of investigators—from people with moderate skills in molecular biology to make TALENS, and high school students to be able to make CRISPRs—to design nucleases that have a high probability of recognizing the desired target site in the genome.

By being able to design the guiding sequences for these nucleases, it’s possible to create double strand, and with further modification, single strand breaks at very specific sites in the genome causing the cell to activate its repair machinery. Depending on the setting, these breaks will be repaired in one of two ways: (1) non-homologous end joining, which can result in insertions/deletions at the site of the break generally leading to inactivation of the genetic element (usually a coding gene, but it could also be any genetic element), or (2) homologous recombination, which can lead to inactivation, activation or substitution if a piece of DNA is provided to serve as a template so that precise nucleotide changes can be inserted into the DNA.

With homologous recombination-based genome editing, a single base can be changed, or a whole set of genes can be inserted. Using homologous recombination, it’s possible to make single base pair changes, but it is also possible to insert at least 15 kilobases of additional DNA at the site of the break (thus allowing one to insert multigene cassettes into a single location in the genome).

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Topics: White Papers

Raising More Capital Through a Regulation A+ Offering [Webinar]

Posted by John Badger on Sep 18, 2015 8:33:59 AM

On Thursday, October 8th, ShareVault, in partnership with Command Financial and Morrison Foerster, will be offering a free webinar presented by Anna Pinedo highlighting how private companies can use Regulation A+ as an exciting new alternative for raising capital.

Now that the Securities and Exchange Commission has adopted final rules amending Regulation A, there are new opportunities to use Regulation A to raise capital or increase liquidity.

Although its availability is not limited to any particular industry sector, life sciences and biotech companies, community banks, and real estate businesses may find this alternative especially attractive. In this webinar, Ms. Pineda will provide an overview of the new rules, focusing especially on Tier 2 offerings, which permit an issuer to raise up to 50 million dollars in proceeds.

Register Now for the Free Webinar!

During the webinar Ms. Pinedo will address:

  • Eligibility requirements
  • Preparation of disclosure materials
  • “Testing the waters” and other communications issues
  • Integration of offerings in close proximity
  • Regulation A as a precursor to an IPO
  • Use by selling stockholders, and
  • Obtaining a concurrent stock exchange listing

About Anna Pinedo:

Anna Pinedo, a partner with Morrison & Foerster, has concentrated her practice on securities and derivatives. She represents issuers, investment banks/financial intermediaries, and investors in financing transactions, including public offerings and private placements of equity and debt securities, as well as structured notes and other hybrid and structured products.

Ms. Pinedo works closely with financial institutions to create and structure innovative financing techniques, including new securities distribution methodologies and financial products.

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Topics: Webinars, News

ShareVault to Attend Rocky Mountain Life Science Investor & Partnering Conference

Posted by Steve Joseph on Sep 15, 2015 9:55:18 AM

Los Gatos, Calif. - Sep 15, 2015 On September 23 and 24  ShareVault will be at the 4th Biennial Rocky Mountain Life Science Investor & Partnering Conference where we are a “Summit Partner” co-sponsor of the partnering forum space at the conference.

The Rocky Mountain Life Science Investor & Partnering Conference, held in Vail, Colorado, is committed to bringing together leading investors, emerging companiesand senior executives in order to cultivate partnerships within the life science industry.

The Rocky Mountain region is the largest and most advanced area between both coasts for venture capital investment in the life sciences, with Colorado ranking in the top 10 among states, garnering more than $1.2 billion dollars in financings and investments from 2011-2013.

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Topics: Events, News

About ShareVault

Simple & Secure Document Sharing

ShareVault offers virtual data rooms for securely sharing documents with third parties. Typically used to share due diligence documents during M&A, partnering, fundraising and other dealmaking scenarios, ShareVault is increasingly being used for a wide variety of other applications, primarily in highly regulated industries, for securely sharing documents with third parties. ShareVault can be set up and deployed in an hour, yet offers enterprise-grade security and scaleability.

Learn More About Sharing Documents Simply and Securely Using ShareVault

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